There are a few ways to tune a load/barrel to produce the best accuracy. Using factory ammo, the only ways to tune a barrel/load are: 1. choose various types of ammo, or 2. to physically change the rifle, either by pressure point, shortening the barrel, or by using a tuner.
By handloading, tuning can be accomplished by changing: bullet types, weight, powder type/charge, cases, primers, and seating depth. Of these, seating depth seems to be key element. Finding the right seating depth involves shooting groups of 5 rounds, starting with a seating dept that puts the bullet ogive about .001" off the lands and going about every .002" backward to about .015". If the sweet spot is found between those two distances, ti can be further refined by going to increments of .001" on either side of the preliminary sweet spot. If not, keep going back until a second preliminary sweet spot is found.
My rifles seem to shoot various bullet types well at the same seating depth, but your results may be different.