It (TiteGroup) doesn't behave well in 38 or 357 mag because of the heat and low volume.
I will 90% agree.
Clearly, TG is designed for semi-auto use. But I did get it to work well with 148 plated DEWC's. Because DEWC's sit deep in the case, the bullet takes up the volume; thus, making for more consistent burns - or at least that's what the chronograph tells me.
Honorable mention goes to 125 JHP's (38 Spl+P). I loaded them up to 1000 f/s (999 to be exact 4" bbl) and they run really nice. Really nice. Gives my Model 67 the perfect little snap with next to no recoil. It's a fantastic loading. I'm going to miss that one when the last of them are shot (soon). BTW, I suspect pressure is a bit beyond +P with this one. Please do your own work ups and never "chase velocities."
On a related note, Hodgdon advertises TG as being non-position sensitive, or however they word it. Well, in my tests with low power 38 Special (lead DEWC's running around 730 f/s), it IS position sensitive. I will give Hodgdon a break on this one though. They were likely talking about how it's usually or supposed to be used - i.e. semi-auto. What I did was an extreme scenario.