I have had very good success with ballistic tips, and the similar winchester CT silvertips, and the rem accutips on deer sized game ( in .243. 7mm-08, and .308 win ), but then again I haven't had to punch them through bone like you have - we take broadside shots probably 95% of the time. We have yet to recover a bullet from probably 15-20 deer shot with any of the above listed bullets.
I agree that a fairly tough bullet should be used in a smaller caliber like a .22-250. the nosler partition in 60 gr would be great for broadside shots at small to medium sized deer, and as the photos show, it does a decent job!!!
Still, for me at least the .243 is about the mimumim that I am comfortable with for deer. It has more margin of error, bigger bullets, and hits harder.