In the early part of the summer I get ticks on me pretty much every day. Luckily the ones around here are the larger ticks and easy to see. I check myself carefully a couple times a day, especially my hair. My understanding is that they have to be on you 24 hours for Lyme to be transmitted.
My wife has been fighting it for about 4 years. At one point she could not even get out of a chair without help. Now she takes about 20 medications a day. Four different antibiotics, on one week, off two weeks type thing. Something to break down the biofilm, something to kill what comes out of it.
I don't think you ever really get rid of it.