All right, I think it is a weird question, but what would you want in an offensive handgun?
1. Accuracy - offense means longer shots. Revolver - check.
2. Power - if we are aspiring to replace a rifle, it better put out like a rifle. Revolver - check.
3. Size - doesn't matter, but bigger is easier to handle recoil and sights. Revolver - check.
4. Capacity - would you attack with a gun that will need to be reloaded soon into the fight? Revolver sucks for capacity, and is slower to reload.
5. Trigger - DA triggers are there for safe transition from carry to shooting. Completely unnecessary if you know you'll be shooting and have gun unholstered. Also makes long shots much harder. Revolvers don't cock themselves, either.
In the balance, a large, high capacity auto shooting a magnum level round is your best "offensive" handgun. Compare to a 10mm widebody 1911, a Glock 20 or Mk 23 with +P or Super rounds. None of those guns give up anything to the revolver, but add capacity and lighter trigger.
So, no, IMHO the right auto would make a BETTER offensive handgun than the best revolver. But both make terrible rifles.