Over the years I've gone back and forth on numerous handgun calibers for target/sport shooting, self-defense, and per department requirements. But like with Frisco, my hands have been beaten up pretty good over the years from officers who can't quite seem to control the direction of their baton swings.
These days, when it comes to handgun plinking I most enjoy shooting .22. For self-defense with handguns I still use a variety of calibers dependent upon the task at hand.