Interesting discussion so far, certainly varied experiences....my experience with the SST was with my 280. Shot a whitetail doe, about 150 yds, hit the shoulder blade and she went down. Normal, I thought, until she got up, shot her again, lung shot down for good. Inspection showed the first bullet blew up and did not even penetrate the shoulder blade. These were factory loads. Had just gotten the rifle and had no time to work up a hand load.
This past season killed a buck with same rifle, 140 AB at 2830 fps, mild but accurate, hit the spine and generated a hole big enough to put my fist through. Distance about 165 yds. Didn't expect that from an AB!!
On the other hand, have killed probably a dozen whitetails with my 7STW, 140 BT at 3425 fps, ranging in distance from 30 to 300+ yds. All one shot DRT and never any damage like that AB.
Used Sierra 140 Pro Hunter for nearly 30 years in my 7 mag, and customized 7X57 Mauser with equally good results, same range of distances, all through and through. For the price and performance I now stay with the Sierras for these applications.