In many areas you wouldn't be shooting any deer with your .243, lowly or not. It's shotgun or straightwall only. I can't imagine hunting anything I can't kill with my 357max, but many times I had that .444 marlin in the field and was comforted by the margin of error it gave me. The .460 is a very useful cartridge in the hunting arena, especially if you have any ideas of going after bigger game than whitetail.