Greetings all. I've owned both the USP but in 9mm and the P220. I've kept the P220 and I favor 9mm over .45 so that says something. My SIG-Sauer P220 in .45acp has never jammed on anything and has extreme intrinsic accuracy in an out-of-the-box handgun. The fixed sights are on and the trigger pull in da is not bad and very good in sa. I believe this is the better of the two for concealed carry, but suspect that in a torture test to the death, the HK might outlast the P220. Still, how realistic is that in terms of the rounds we are likely to fire? Best to all.
