I'm cross dominant (left-handed, right-eyed), & I find that in force-on-force training my most natural two handed shooting position is a loosley modified Weaver and the gun held at a 45 degree angle from vertical. It feels a little unnatural to twist my left arm the extra 15 degrees to get the gun vertical. We always work on the premise that if it works, don't fix it, and so far this method works well for the combat shooting that I spend most of my time doing.
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It is far better to dare mighty things, though riddled with failure, than to live in the dull grey of mediocrity.