DA revolvers don't have manual safeties, and DAO pistols rarely have manual safeties. So it is not a huge stretch to accept a partially-cocked striker fired pistol with no manual safety. And the large numbers of Glock, XD, HK, Walther, and other pistols clearly show that many many shooters agree... and I understand that some of these are actually fully cocked, but that is a different discussion.
I love shooting my 1911, but it is a range gun, a target gun, a steel plate gun. For defense purposes I chose a gun with no safety (Glock, Walther PPS), or a DA/SA gun with the safety off (FNX), or a DA/SA decocker with no safety (SIG).
1911 fans often tell me that getting comfortable with a manual safety is a training issue. Fair enough. But learning to comfortably and safely live with a no-manual-safety pistol is also a training issue.
Like many things, it comes down to personal preference and what each of us is comfortable with. There is a right answer for me, and there is a different right answer for you, but there is no one right answer for everyone.
Jim