Any caliber capable of taking down a deer will ruin meat it is a matter of hitting the deer in the right place.
You can shoot a deer in the arse with a .223 and have it run away and never find it and ruin all the meat or shoot a deer in the arse with a .270, knock it down and get another one into it in a place where one may actually want to shoot a deer.
The thing to do with this operation would be to go out and shoot a deer in a reasonable place such as the heart or lungs, kill it effectively with the first shot.
You can shoot a deer in the arse with a .223 and have it run away and never find it and ruin all the meat or shoot a deer in the arse with a .270, knock it down and get another one into it in a place where one may actually want to shoot a deer.
The thing to do with this operation would be to go out and shoot a deer in a reasonable place such as the heart or lungs, kill it effectively with the first shot.