Howdy
ALL single action revolvers with a base pin secured by a transverse, spring loaded latch can have the pin back out from recoil. Colt, Ruger, or clone. And it does not have to be handloads. My first experience with this happening was with my 45 Colt Blackhawk and standard factory loads. With a Ruger, there is a spring plunger at the rear of the cylinder pin. The purpose of the spring plunger is to shove the transfer bar rearward as it rises, so it does not hang up under the frame mounted firing pin. If the pin jumps forward, the spring plunger no longer pushes the transfer bar back, and it can jam under the firing pin, which is exactly what was happening to my Blackhawk. Took me a little bit to figure out what was going on.
I have also had this happen with my 2nd Gen Colts, and a couple of Uberti Cattlemen. Yes, full power Black Powder loads with their heavy recoil can make things worse, but the first time it happened was with factory loads in my Blackhawk.
There are three solutions to the problem.
1. Put in a stronger spring.
2. Replace the cylinder pin with one from Belt Mountain.
3. Fit the pin properly to the latch.
The real reason this usually happens is the latch is not properly fitted to the recess in the pin. Stronger springs and new pins will address the symptoms, but the real cause is the latch does not engage the recess in the pin properly.
I have replaced the pins in my old Blackhawk, two Vaqueros, one clone and three Colts with Belt Mountain pins. I also had to fit the pins a bit in some of these guns to completely stop the pins from jumping out.
Belt Mountain also makes pins with a locking set screw. I do not recommend this option. It is too easy to lose the tiny allen wrench for the screw, and overtorquing the screw slightly will bend the pin just enough to cause binding. Been there, done that.
Here is a photo of a standard pin in front and a Belt Mountain pin in the rear. I think the standard pin is a Ruger, but I'm not entirely sure at this point. Notice the Belt Mountain pin only has a recess cut across the pin, while the standard pin has a groove going completely around the pin. The Belt Mountain design is better, because it leaves more surface area for the latch to engage. Notice there is a tiny flange on the Belt Mountain pin. There is a clearance cut on that flange, not visible in this photo. The clearance cut is for the barrel, to keep the slot aligned to the latch. Yes, it is easy to accidentally jam the pin in place when replacing it if you are not careful to line it up.
One other thing. The 'original model' Vaquero and New Model Blackhawks had a pin long enough that it could not accidentally fall out. In fact, to remove the pin you had to take the ejector housing off to clear the pin. New Vaqueros, Colts, and clones have shorter pins, and they will happily fall out of the gun and get lost in the grass at the worst time.