The classic load for the .45 Colt is a 255gr bullet with a rather pointed round nose (some say conical) and a small flat tip. This is the factory bullet used since the introduction of the round in 1873, and for a very long time was the only bullet factory offered in that cartridge.
My personal preference is for a 250gr SWC design and those that are, or closely resemble the Keith design work the best, in my guns. I prefer the large flat point and the sharp shoulder of the SWC design as it seems to work well transmitting energy and also generally makes clean holes in paper.
Most of the 200gr SWCs are designed for the .45ACP. They can be used, and will do well, but they are not ideally designed for revolver use, which somewhat limits their applications.
My "stout" working load for the last 3 decades has been a 250gr SWC over 10.0gr Unique. Like me, the load is old, dirty, and it smokes.
but it hits what I aim at, hits hard, and isn't painful to shoot. Velocity from my 7.5" is approx. 1100fps. This is also the max listed load in the old (1970) Lyman manual, using a Colt SAA as the test gun. For a Ruger Blackhawk, its not near what the gun can safely take so there's no worries there, HOWEVER, ALWAYS work up to any load carefully, just to be safe.