I've owned the Marlin Model 60 and the Ruger 10/22. The 60 disappeared many years ago under mysterious circumstances, but I enjoyed shooting it.
The two rifles have a different feel when shot, the Ruger just goes bang and that's about it, I seemed to be able to feel the bolt coming back in the 60, kind of a "sliding feel".
With my two rifles, the 10/22 stock was thicker and fit my hand and shoulder better, and more of a "real rifle" feel. The 60 had a slimmer stock and always kind of felt like a toy.
I dislike the tubular magazine on the 60, for small game hunting it can be a pain. In GA you have to unload within 50yds of a road open for travel on public land, so I was forever taking the tube out, pouring the cartridges out, then reloading them, etc. With the 10/22, you simply pop the detachable mag out and pop it back in when you are ready. Additionally, I like being able to load multiple mags for the range and plinking.
I also think that the detachable magazine is a bit safer for new shooters, as the rounds aren't hidden in the tube. Pop the magazine out, clear the chamber, rifle is clear.
Accuracy wise, I didn't see any difference in the two stock rifles.
You won't go wrong with either, it's largely a matter of personal preference, but I like the 10/22.