It may help to know what you mean by disabled. Any idea whether strength, range of motion, or coordination are affected? Or perhaps disabled means wheelchair bound?
My first thought was the M&P Shield EZ9 or 380 also, not because I own one, but they are supposedly easy to load and rack.
For small hand size, Kahrs do have slim grips. I EDC a kahr, and in the smallest model the short recoil spring needs to be stiff, so it can be difficult to rack. So a larger one like Dfariswheel mentioned would do better. For being described as a revolver-like trigger, the trigger pull is much lighter than a small revolver's trigger pull.
If she lives on her own and doesn't have anyone to help her load mags, maybe a revolver would be easier to load. Although I hear the shield EZ series are supposedly easier to load, you would need one hand to pull down on the spring tab (like 22 pistol magazines usually have) and the other hand to slide rounds under the feed lips. If she's got 2 hands or a helper maybe it's a non issue.
For revolvers, she could open up the cylinder (although the latches are made for right handers), set it down on a table, slide some rounds in, and close it up. Revolver reloads in an emergency could be difficult one handed depending on her physical challenges. The M&P Bodyguard revolver has an ambidextrous cylinder latch, but the trigger pull is just as stiff as the usual J-frame, along with the stout recoil.
Trigger pull on the smallest revolvers (J-frame size) can be tough depending on what deficits she's experiencing. Sometimes the first trigger pull on Double Action/Single Action semi autos can also be stiff like on a Cz75, Beretta 92FS, Sig p226/229. Again, not sure what the limits of strength are as it affects her ability to pull a trigger or hold a heavier gun.
Best of luck to you and her too.