Hard telling what you rifle will like until you try it. For 308 case's I like 4064, Varget, R-19, H414, H 4350 and IMR 4350. The powders I like in the 308 are about this speed but then some a bit faster too, 30 cal bullet's. In my 243's I like H4350, H414, Varget. Seem's they all work. About all your changing is bullet size, 6.5 CM case is about the same size as the 308 if I heard right.