The bottom line is where the round hit and what damage it does within the rib cage, not how much blood it leaves on the ground. I've shot a couple dozen deer over the last 20 years and have had deer shot through and through go over 150 yards. In most cases I've used Nosler Ballistic Tips, this year was no exception. The spike I shot this year had the round enter the last rib on the near side and stopped just under the skin on the off side, he dropped dead on the spot, 300 yards away. Last year I killed a spike at about 10 yards with my .45 ACP, the Federal 230 grain Hydrashok punched a hole in the ribs and stopped in the off shoulder, it went down in two steps. One year a friend of mine blew out the side of a buck with his 7 Mag, that animal went a mile with half his guts dragging along the track. Another friend once shot a fork with his 06 using a 165 grain Ballistic Tip, hit too far back, we tracked it through my swamp until I was able to wingshoot it at about 40 yards through the neck.
I generally shoot a 7 mm Rem Mag, 150 grain Ballistic Tip at 3000 fps out of the muzzle. After a couple of ruined shoulders, wherein the shock of the bullet blood shot the meat on entry and didn't fully penetrate, I switched to Partitions of the same weight. I then shot a buck in the lungs at 100 yards, punched a hole clean through, the deer, stopped, snorted, ran about 20 yards and died just inside a line of pine trees. Lungs trashed, dead deer. I eventually realized that at no time, when I did my job, did the bullet actually fail. You put a decently constructed projectile into the heart/lungs of any deer and its going to die. If you don't take care to do that no matter how big a hole you put into the thing you've got a nasty wound and a tough tracking job.