Something to be aware of w/ either factory or handloaded ammo, is that if you push the bullet further into the case (aka set-back), this will tend to increase the round's pressure when fired. This can occur from by repeatedly rechambering a cartridge - or simply by not handling your ammo properly.
I've never witnessed a kaboom due to set-back, but have read advisories that were issued to police departments regarding this issue. There have apparently been a few incidents of detonations occurring in service pistols, when using ammunition that was frequently rechambered.