don't do it
Firearms chambered in .22 mag are for .22 mag ONLY. There is no interchangability in this ctg. Any advice to the contrary is dangerous.
Twenty-2 mag is not cheap, esp anymore, but it is not a plinking caliber.
It is ideal as a upgrade in power FROM a .22 lr, in a rimfire hunting/woods gun.
It shoots considerably flatter in a rifle, and hits considerably harder in a long bbled revolver, than any .22 lr. The new, premium light bullets add another dimension, that I have not yet explored.
I was opposed to the .22 mag till I inherited my Dad's 6" Ruger single-6.
It will anchor a chuck or coyote much better than a .22, and though not recommended, more gun for SD if needs be. Ammo is still cheaper than a .32-20 or .38, even w/ reloads. (maybe not w/ lead ammo) FMJ ammo penetrates well if you think you need it, hollow points are very destructive, esp from a rifle.
My single-6 is lighter than a compareable .38 k-frame or SAA, and 100 rds of ammo weigh near nothing. You can still shoot half a box at cans and rocks and not go broke, and have 20-30 rds for the pot or to finish your wandering.
You can shoot a .22 lr cheaper, but if you carry more than you shoot, and when you do its at more than cans and paper, the .22 maggie starts to make sense to me.