I have been shooting Bullseye pistol for the last three years. What I have noticed about 22 lr's is that the M41 S&W seems to be the most common among the old timers. I have seen a few High Standards, but they are definitely scarce.
I got a great deal on this rare M46 with 5.5" barrel, which is a very rare variation of the M46. I had it drilled and tapped, probably ruining any collector value, but so what, I want to shoot it. I did shoot it this month in a State Championship and it shot better than me.
The S&W M41's are very accurate, good ergonomics with factory grips, and the triggers are wonderful. They are also reliable and parts are available. This is a strike against the High Standard pistols, the owners tell me the magazines wear out and replacement magazines are $100 apiece, or something like that.
I have seen a good number of Ruger MKII's and MkIII's. This is a Ruger MKII of mine. The Ruger is an inherently accurate pistol, if you get one with a good trigger (and you have to look) and you put on a better pair of grips than the factory grips, the pistol will shoot well. It is also cheap compared to the M41 S&W and I think the combination of price, good enough ergonomics and trigger, and excellent accuracy is why I have seen these are on the firing line. The greatest strike against the Ruger pistol, in my opinion, is the difficulty of cleaning the thing. Competition shooters don't want malfunctions due to dirty pistols, so they tend to clean between each and every match. Take down is easy, but not obvious. Reassembly has always been difficult, getting that hammer strut aligned with the mainspring is particularly frustrating and not intuitively obvious. You can't see what you are doing, the hammer strut is hidden in the frame. Each time I do it, I have to relearn the procedure after fumbling around for five to ten minutes. The situation is even worse with the MKIII. The magazine safety is a terrible idea. You have to put the magazine in, pull the trigger, take the magazine out. When trying to get the hammer strut in line with the mainspring, you have to do this about 20 times, and with the MKIII, you forget the sequence sometimes in your frustration.
Rarely will you see something really expensive like this Feinwekbau AW93.
This is a very beautiful, well timed, maxed out bells and whistles pistol. It is so expensive I could only afford to take pictures, which is probably why I have only seen one.