I carry a 10% oil based OC "borrowed" from the Marine Corps weak side trouser pocket. I don't want a belt holster for OC, I just think it makes me stand out too much if I tuck my shirt. IWB is uncomfortable as hell, and I like to carry the same way no matter how I dress. I know you can't always get away with that, but I like to get in routine with OC as it's too easy to not take as seriously. That being said if I had to keep changing it around I would be prone to forget it or to just say screw it. I have trained to draw pistol and OC at the same time, OC weak hand and pistol strong hand, though I have gone over some threat recognition drills also. I like to incorporate shoot/no shoot situations, escalation of force, and also skipping force escalation and going straight to lethal (I think that last one is important, if someone is obviously likely to kill you very quickly skip reaching for OC and just draw a spare mag with the pistol).
My rules for carrying it... this is pretty hard for me to explain. Just because by a technicality of the law someone may be using deadly force bare-handed in some states doesn't mean you have to shoot them. If someone was coming to wail on me with blunt force weapon I would probably draw OC with my CC. Mind you I hold myself to a higher standard than even the law sometimes prescribes. I don't want to kill anyone but I will if I have to. That being said, I may choose to attempt to save the life of my attacker even if I could get away with taking it legally. If I get myself killed for doing that, then God will take care of it. Anywho, firearm I definatly skip LTL. Knife, it would have to be about a 2" blade or less before I skipped LTL. Melee, depends on how close, how many, what type, so on so forth. If I have time to use LTL I will in that case. LTL is a primary many times in NC as the state is pretty restrictive with some of the places you can carry, so LTL is primary in those places.
Anywho, this is what I use but I'm kinda excited to see what others post. I have actually thought of using a rubber bullet in the chamber as I carried or other LTL devices. I'm open to other LTL possibilities so keep tactical practices coming. Hope this helped