Eye dominance is "relevant" in finding the individual workings of one's dominance or preference of hand to eye sighting. There are right-handers with left dominant eyes and left-handers with right eye dominance. Changing hands is an option to correcting what our brains are telling us. I can shoot with my astigmatism by closing my alternate eye and practicing. Everything takes practice to set the brain's expectation. Try placing a piece of paper over your dominant eye and use the other eye to sight with the front sight. Try the other configurations and see if there is a possible compromise. Try all angles for the direct line of sight so you do not have to turn your head sideways to your line of sight.
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