if I had the need for another full size gun, I would have t probably pick the 9mm/.22TCM combo from Rock Island. Yes it's only a 17+1, but man that .22TCM looks like fun for a reloader. I say this because I already on a CZ and a CZ clone, and I wouldn't ever give that up as my bedside pistol, the clone anyways....it's pretty hard to justify buying a real CZ anymore after owning Canik/Tristar clones, except for resale value. I like the Tristar trigger better and the 200-300$ less price tag, just don't get a tristar with an alloy frame and a blue finish, bad combo.
Canik-55 TP-9 18+1 9mm 350$
Tri-Star S-120(steel-frame) 17+1 9mm 380$
those are my recommendations for an affordable home defense pistol. I have since made a very small 9mm AR with a 5" barrel and diamondback "nite-sites" that stays next to the bed(32+1), but still rely on the Tri-Star T-100 pistol to save my buns if ever in a quick jam.