I fully admit to not reading through all 7 pages of this, but I did read through several and thought I would throw in on it.
In your initial post, based upon the table you presented I would choose the 25-06. The reasons are several. In my case I have a ton of once fired '06 cases in which to neck down. This makes things cheaper to keep on hand, and it is VERY easy to distinguish between the two should they all end up mixed in the bottom of my ammo box. Next it has a very mild recoil for a caliber which can use close to 60gr of powder. Even with top loads my daughter at 9yrs old, and my oldest grandson when he was that age had no issues putting it to task on thier bucks. For me it has reached out to over 400yds and put everything I took aim on, down with no issues. Accuracy has been phenonimal with the one we have. I have used a 115gr Partition as the general load for 20 something years. It leaves the barrel at around 3150fps and the drop at 400yds is around 18-19", and fits the Leupold duplex retical almost perfectly at that range. Simply put the top of the bottom post where you want the bullet to go and let her fly.
As to the efficiency, well I think that is somewhat of a broad comparrison. Not that by using 30grs of powder to get the same basic performance as using 50 isn't efficient, but just like some who prefer a 38 over the 357, it simply is to me a personal thing. I'm not, at least at this time in my life, overly concerned with the added powder to get where I want to be. In the recoil aspect, yes I CAN see where less is better with everything else being similar. There again though, to some recoil is an issue where to others it isn't.
Ok so I am a bit biased towards the 25, in fact I built the Ackley version for myself and passed the standard one over to my daughter. Still though I am running the 120gr bullets in it, and again my oldest grandson just recently used it to drop his first 10pt buck at just over 300yds. It is using a LOT of Ramshot Magnum along with a 28" barrel to make a VERY flat shooting rifle. Yes it WAS built to reach out and touch things a fer piece out, but I have also laid waste to a bunch of hogs up as close as 30' with it. (I thought they were pretty dumb to stick around under the fallen tree, but took full advantage of it.)
Before I built it I looked over a LOT of things, one of which was the 6.5x55 and the .26-08 before it was the .260. I thought of going with a short action, and something which would work with a 120-140gr bullet, and around 40grs of powder. The bullet selection is huge in this caliber, but after listing everything out I simply couldn't justify it due to already having a M96 in 6.5 and the .308. So, I looked at the .257's and decided that the Roy was simply too expensive for my taste anyway, and that I wanted just a touch more than the standard version 25-06. I had the breech cut longer to allow it to be set back should i toast the throat, or possibly want to rechamber to the standard version.
All this said though, I fully believe as mentioned that choosing a "best" among the long list of main, and sub calibers derived from them is about as easy as picking THE best vehicle that would suit everyones needs. While gas milage might be wonderful in a sub compact, pulling my tractor down the road with a Hyundai is a whole differnt thing. My 1 ton might not get the best milage, but it is the tool I need for the job. After all, choosing the proper tool for the intended job IS what we are talking about in the long run, right?