I own a CZ550 AmSaf in .375H&H. It is hands-down, my favorite commercial/sporting rifle.
Mine is stupid accurate with even cheap (for .375H&H) Rem Express 270gr soft point ammo.
I have used a CZ-550 in .375 H&H mag. on five african hunts and shot most of the 61 animals there with it and they all died with one shot, except two that required a finishing shot to shorten the tracking. i have never felt the recoil when shooting large animals close up. I liked that rifle so much that I bought a CZ-550 American in 6.5x55. eastbank.