Primarily urban:
- M&P40C--just feels right. Lo cap for CC, hi cap for range, open carry and HD. Gives up very little to non-compact model. Runner up: Ruger SR40C for same reasons.
- S&W 65LS (Lady Smith) .357 - 3" K-goodness, what's more to say?
Primarily rural or wilderness:
- DW 1911 Guardian .45, or CBOB 10mm north of 40th parallel out west.
- Ruger New Vaquero .44 Sp Sheriff, or Super Blackhawk .44 Mag 4-5/8" if north of the 40th parallel. Rugged reliability and punch for most anything two or four legged. If the idea is both auto and revo, I'd think of a 4-5/8" Blackhawk .45/.45ACP convertible for partial ammo sharing with the 1911 45.