If I could only have one handgun? Let's hope that day never dawns, but if it does, I'd go for versatility, since the gun would have to perform more than one function.
A good .357 revolver (Ruger, Taurus, used S&W or Colt) would be my choice. My wife and I could both use it for self defense (she's not a gun person, and I'd feel better with her handling a revolver rather than an auto). I could also use it for small-game hunting (and deer hunting in a pinch), plus I could shoot .38 Spl. cartridges in it. A 4" bbl. would be about right.
DAL
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Reading "Capitalism: The Unknown Ideal," by Ayn Rand, should be required of every politician and in every high school.
"Guard with jealous attention the public liberty. Suspect everyone who approaches that jewel. Unfortunately, nothing will preserve it but downright force. Whenever you give up that force, you are ruined."
--Patrick Henry, during Virginia's Convention to Ratify the Constitution (1788)
GOA, JPFO, PPFC, CSSA, LP, ARI, NRA