Jim243 said:
...The only effective method I know of that will totally disrupt the brain and nervious system is a Taser....
Or a direct hit.
iMagUdspEllr said:
...Why can't I inquire about hydrostatic shock on a gun forum?...
No reason why, but the bottom line is that hydrostatic shock at the velocities of handgun ammunition is non-existent or so negligible as to be a non-issue.
Instead of chasing the Chimera of hydrostatic shock, for self defense purposes one will be best served by getting good training, practicing, being able to manage your weapon well and shoot accurately, and using good ammunition all improve your chances for a good outcome. But there are no "secrets of the ninja", and you will need to be able to deal with your problem until it is solved.
In real life there are many variables. Randomness and chance will play some role, to some degree, in the outcome of any shooting event. There seem to be some general themes, however.
[1] Shot placement is king.
[2] As I recall the tables tabulating results of actual events on the street, for at least .45 ACP all JHPs performed close enough to the same, and all JHPs performed uniformly better than FMJs.
[3] Adequate penetration is vital. (But excess penetration doesn't do anyone any good.)
[4] Bigger holes are better than smaller holes.
[5] Sometimes a .32 in the thigh has stopped a fight. Sometimes 10 rounds of .45 ACP +P, JHP in the thorax haven't.
[6] With a handgun, there will always be compromises -- size, concealability, and manageability against size and power of the cartridge.
[7] There are no magic bullets.