In 2008, my brothers and I crammed 3 antelope, 2 coolers, 2 tents, 3 sleeping bags, all of our shooting supplies, 3 folding chairs, a tool box, mini air compressor, and 15 gallons of water into my Flare-side, short-bed Ranger (41"x59")... and the antelope didn't have anything packed under, on top, or around them. (Additional crap was in the back of the cab.)
Gaining the additional 2 feet of width with a full size truck makes things that much nicer. (Unless you put a bed box in the bed... then you've got my bed, turned sideways.)