Many good options. I like the nice built-ins posted by NightSight, perhaps they'll update designs to include 2009 model trucks soon.
Unfortunately, I can't always carry a firearm because I work in a hospital and frequent my kids' schools, etc. Ideally, I would carry more often, but I don't because I hate the feeling of leaving a loaded firearm in a parked car for 12-16 hours per day. Also, I have secured, quick access weapons in the house, which I'd also like to have in my vehicle without having to carry back and forth in my daily routine.
Previously, I would toss my 357 in the magazine pocket behind the passenger seat. Ideally, I'd like a very thin-profile top loading box, electronically activated, which could be mounted behind the passenger seat, or in the driver's door. Most of the boxes I've seen are on the bulky side, and would be easily noticed by passengers, etc.
The integrated console safe would be ideal if it could be accessed flawlessly in less than 3-4 seconds. My home safes pop open in 2-3 seconds with my gun drawn and aimed in <5 seconds.
To me, the most vulnerable time in a vehicle is when parking, entering and exiting your vehicle. But more convienient would be the ability to choose exactly when and where you conceal your weapon, versus safely leaving it in your vehicle.
I like the first aide kit idea a lot, and might paint one of my current digital lock boxes and then bolt it to either the floor or back of a seat in my truck. I love the combination of rapid-access security and psychology in that concept. My current boxes can fit 2 guns in width; however this makes them a bit fat--I'll have to look for one that is a thinner profile.