.45 ACP?
I saw a Youtube video back around 7 years ago of a guy with a 1911 in .45 ACP shooting a good sized hog. The pig was getting corned in a fenced area and decided to charge the pistol holder, the man fired and the pig felt the hit and ran the other way, then saw he was cornered and charged again, boom another hit, this went on and on until the pig figured out that charging the shooter was a bad idea, and he was undoubtedly loosing blood too.
I no longer remember the details but it convinced me to use something more powerful, I have a Ruger GP-100 in .357 mag, and a Ruger Super Redhawk in .454 Casual that I would feel more comfortable with. And yes, I do own a Glock 21 in .45 ACP. I suppose I could just machine gun the pig with my Glock, empty magazine after magazine, or try one of the new heavy bullet designs.