My wife finally expressed an interest in shooting some kind of firearm for the first time in her life. Up til now, she has never so much as looked at a gun other than to move one if she was dusting or something. So, I showed her once again my collection (which she refers to as "all those guns") and explained to her the relative merits of each one. She had no desire to even hold a rifle of any kind. After showing her the various handguns and their ammo, she allowed as how MAYBE she could shoot the 22 magnum. Cool, so I took her out with an H&R 676 with a 7.5" barrel. Thish was my very first handgun I had ever fired back 30 years ago. I have put thousands of rounds through it and it still has a sentimental attachment to me.
Long story short, I was astounded at how well she could shoot it. Mostly I just wanted her to be safe and experience the feel of launching a bullet. Shoot, by about the 3rd shot, she was hitting pop cans from 25'. By the second cylinder, she was hitting them about every 4 out of 6 shots. After about 30 rounds she could hit a pop can nearly every time.
I don't think she will ever be a fanatic, but at least she knows how to shoot and can understand the enjoyment that the rest of us get from it. She was not interested in shooting anything else, not even a 38. That's fine. She now proudly shows "her" 22 mag pistol to her friends, although she does seem to be mystified when she hears about how it takes hundreds or thousands of practice rounds to become proficient.