I think that even with a marginal shot into the body cavity, the shock to the system would be a whole order of magnitude above a standard lead bullet, and better than a lot of hollow points. The way those things are going to rip through body tissues will be horrendous, the bleeding will be incredible, and out of a .357 or .44 would be absolutely devastating.
Again, though, I think that this whole concept is iffy, and performance as expected is the key.
I maintain that the key is use a good general purpose combat load that you can expect to perform well under almost any circumstances, and take your chances. Counting on a glaser to perform exactly as it is supposed to makes exactly as much sense as taking head shots, hoping to connect eventually, rather than putting a couple of rounds in the upper torso.