.22's, to me, have always been more of a utilitarian firearm than anything (I've always been more interested in larger calibers and thus have enjoyed shooting them more). That being said, my favorite .22 handgun is probably my H&R Sportsman simply because I find top-break revolvers to be interesting though I must admit that I've picked up a couple of Heritage Rough Riders in the past couple of years and they're an awful lot of fun (though I really like them with the magnum cylinder).