Video of revolver shot underwater shows escape of gas
I ran across this video which shows there is quite a bit of lost gas between the cylinder and the barrel when a revolver fires: http://i.imgur.com/AgMgPPM.gif
I shoot a 4" 625 revolver as well as a Kimber 1911. The 1911 gets about 50fps more with my normal load. Results can vary this much one gun to the next. You will lose some because of the gap between the cyl. and bbl.