Think outside the box
You don't need a new caliber, you need a new rifle!~
Hunting rifles are carried 99% of the time, and only shot 1% of the time, OR LESS!
A new, lightweight, short, and quick handling rifle is the nicest gift you can give to yourself! There are lots of custom options, or factory rifles that foot this bill!
A rifle that weighs 7 pounds max, 6 1/2 is better, 20-inch barrel, really good trigger or get a Timney, and in a shorter cartridge maybe, which can come in a shorter, thus lighter action!
I have a rifle like that, but mine is a medium bore for other game, but you could get a cartridge for deer that is suitable for your hunting style! Remember, that style will change over the years, one day you may find yourself in some far-away-land, and a rifle that is diverse can follow your trail!
The scope is the next option that makes a huge difference!
A single power, light weight scope is best, 4X is all you need! If you can't hit a deer with a 4X scope you are shooting too far! I used to shoot 900 yards with iron sights in competition, so I think you can hit deer with a 4X scope ... you don't need a spotting scope on your rifle like you see these days! A scope is for shooting, not for looking ... that is dangerous, use binoculars for looking!!! A single power scope has less parts, less openings for water or other stuff to get in, and is lighter, smaller, and keeps the overall weight down.
Next, is scope rings and mounts. Here you can save weight again, with one pieces rings, and light mounts.
Take your time, research the options, and put a rifle together for a life-long relationship, and a unique friend that is all yours!
On the upper end of the spectrum, this Kimber is a great example of light, reliable, and easy to carry, great to shoot! Get it in 25'06 OR .270 Win. and you have a perfect deer rifle! I handled one at the NRA CONVENTION, IT IS WONDERFUL!
http://www.kimberamerica.com/rifles/model-84l/montana
On the less money end, but still lite and a great shooter:
http://www.tikka.fi/t3models.php?lite
Good luck with your choice!
Hunting rifles are carried 99% of the time, and only shot 1% of the time, OR LESS!