As has been said indirectly, above, with your gun on the half-cock notch, it will function EXACTLY like the decocker model at the start, and be at least as safe. The decocker versions doesn't have a safety! Many guns with decockers don't have a safety that can be easily engaged, and I can tell you from experience and from watching other shooters, most of the safeties on decocker guns aren't used. (That was case with many 3rd Generation S&W semis.) And some guns don't have a safety lever at all. Several of the SIGs I've owned come to mind.
If you're going to always start from half-cock, and decock to half-cock, it's simpler and easier to use the decocker mechanism, and not worry about the safety. You should have had one in the factory box. If you didn't I suspect CZ will send you one for nothing. Deactivating the gun, when you don't have a decocker mechanism installed, requires that you manually decock the gun or use the safety with the hammer fully cocked -- otherwise it remains cocked but not locked.
Your CZ is equipped with a firing pin block, that won't allow the firing pin to move unless the trigger is pulled fully to the rear. Are you comfortable manually decocking the gun? Since you must pull the trigger fully to the rear to release the hammer, you will also briefly bypass the firing pin block mechanism while doing that. The likelihood of a negligent discharge while decocking is pretty small, especially if you practice, but installing the decocker mechanism bypasses that potential problem altogether, by not requiring trigger movement.
With proper practice manual decocking is very safe -- especially if the gun is pointed in a safe direction (rule #1). But so is carrying a weapon cocked and locked. And, more importantly, even if you COULD use the safety when the hammer is fully down or on the half-cock notch -- you gain nothing in terms of added safety by doing so -- but you make the process of putting the gun into action both slower and more complicated. And there are time, in personal and home defense, when you don't want to have to be confronted with slower and more complicated processes. (As noted in prior responses, if you try to use the trigger with the safety on and the hammer on the half-cock notch, it WILL work, but you could damage the gun. And if you're nervous, dealing with a threat... who knows what's going to happen?