6'1" 245 and a member of the donelap club (my belly done lapped over my belt). I use an Alien Gear IWB holster at about the 3:30 position. I have the cant adjusted so as it leans my Glock 19 more forward (muzzle angled farther back) some. This puts it more in between my 'love handle' and my ribs and the end of the holster out of my hip fat when I sit down. I've tried it in different positions/cants and this is what works for me and I find it very comfortable whether standing, sitting or even while in my car. My draw is still smooth and natural (for me). Also, it doesn't print at all even with a dress shirt tucked in; even while reaching, bending or twisting. I have plenty of "soft tissue" to help conceal it.
I tried it in about the 4:30 position and I noticed that mag plate would either press against seat backs and press forward causing the holster to twist and be uncomfortable or, if the back of the chair is curved much at all, end up between me and the seat back pressing into me.
I tried it in about the 4:30 position and I noticed that mag plate would either press against seat backs and press forward causing the holster to twist and be uncomfortable or, if the back of the chair is curved much at all, end up between me and the seat back pressing into me.