Hate to admit it, but...I use several handguns for CC purposes....clothing choices and the anticipated travel environment determine which get to go for a ride. But I do think RickB's suggestion, "I believe in the theory of always carrying a gun with the same manual of arms." is a far better idea if TSHTF.
All but the 1911, below, have the same manual of arms for at least the first shot...a long DA trigger pull.
In town = S&W M60 .357 or a Sig M11A1 or P225 in a Three Persons Open Top OWB
In the city = Sig 1911 RCS .45 in a Askins Avenger OWB (52 years of carrying this one, mitigates against using the same type of manual of arms idea.)
Clothing limited = S&W Bodyguard 380 or the M60 in pocket or an OWB
Farm = whatever I'm shooting for the day and just for the joy of it!
Best regards, Rod