All I can do is express my deepest sympathy for your loss, and greatest happiness for your hanging on to what's truly important.
What your experience does for me, though, is to completely stop my complaining about propellants such as 4227 where a double charge is impossible. I was apt to whimper and whine about compressed loads below max, now I stop my whining. Mostly because I have NO experience with Unique, I've always mistakenly equated it to Bullseye--doesn't matter why and doesn't matter too much that this is wrong--the point being, I've generally assumed it to be a faster, small case powder. Thing is, for big loads in big cases, it looks like it may not be the best choice where mistakes can be made--and that's all of us, everywhere.
I'm really warming up to the expensive, inefficient 300-MP, 4227, No 9 type propellants where you do your best to jam 24 gr of them into a case that they barely fit into, hoping to score near-max performance. With a light on your press, there's no way a double load will get through the system--you'd have spillage all over the place.
Of course it's not certain if you even had a double--could have been any number of factors. I've blown out primers left and right with 800X, and just today I had a primer anvil stick to the bolt face of my Grizzly preventing the next round from going home. Not the first time I've had primers blown out of cases with Starline brass and 800X, with charges 15% lower than other folks are having great fun with. Mysteries of the handloader's art.