Is there a reason why you're limiting your choices to those chambered for .45 Long Colt? You will have a much larger selection of revolvers to choose from if you also consider those chambered for .44 Magnum/Special and .45 ACP/Auto-Rim.
Personally, .45 Long Colt would be one of my last choices for a defensive DA revolver due to its small rim. You see, the rim of this cartridge is only .032" larger in diameter than the case. This is because the .45 LC was originally designed for gate-loading SA revolvers where the only function of the rim is headspacing. While the .45 LC's rim is more than enough for headspacing, it can sometimes "jump" the extractor of a DA revolver tying up the gun until the offending case is removed (not and easy or quick task) .44 Special, .44 Magnum, and .45 AR were all designed from the get-go for swing-out cylinder revolvers and, as such, have larger rims. Those cartridges along with .45 ACP in moonclips provide a significantly larger surface for the revolver's extractor to bear against and thus allow for more positive extraction.