Gator Weiss, you flatter me, thank you. I have been deeply involved in the ML game since 1970.
My experience with the CW style rifled muskets is limited. But, I have known (past-tense, many are dead now) many of the top shooters with them. I can tell you this: there are fewer shooting disciplines where the participants experiment more than with those muskets/minies/powders/lead alloys/chants and incantations, etc.
I will say this, most, if not all who are going for accuracy, end up with the tried and true powder charges. Going hell bent for big bang gains nothing except smoke and recoil. (remember the CW rifle musket was designed to INCREASE felt recoil so the guys in battle would know when their gun when off) Most experimenting revolves around bullet style. I believe the most popular usually ends up with original style.
Understand, a .58 cal. very heavy bullet hitting a living target is a very formidable thing. Shooting the normal charges in the 50-60 gr. range is deadly plenty enough. By trying to go to 90 gr. or whatever you are leaving the world of traditional shooting and entering into a realm of problems. That is not what the CW rifled musket was designed for.
If you want a big bore, big banger, get, or have a good builder build you something like that. A custom Hawken in .58/.60 cal would be fine with the right twist and such. I have seen some up to a full 1.0" bore. With a good barrel and proper build you can stoke them up (almost) as full as you want.
I shoot a .54 Jaeger with 75 gr., patched round ball. And, I can tell you, going over that makes for very uncomfortable recoil even with the rifle weighing more than 10 pounds.
My bottom line advice is to go with what works for you if it is safe. Also examine what you want to do. If you want an elephant gun, build or buy one that loads from the back end. If you want to enjoy old guns in the traditional way. Then do it in the traditional way.
edit: hope this helps