Not when you reload. So to answer your question, no.
I'm with you guys (Don P, 44 AMP, and others) that pay almost no attention to loaded ammo for gun purchases.
But you do need to know what you're getting yourself into for reloading components and equipment.
Buying a Russian Nagant revolver 15-20 years ago would have meant for some seriously frustrating endeavors in tracking down affordable dies and loaded ammo as a source of brass.
Even today, buying an 1886 Lebel rifle means for some extra steps and/or equipment in the reloading process. The original chambering used .323-.325" hollow-base projectiles in a .329" bore. To load for it now, you need to cast custom lead bullets, or swage down .330-.338" jacketed bullets.
Buying a Mini-30, SKS, or AK is easy, and reloading components and equipment are easy to find. However, the rifles toss your brass 900 yards while beating the crap out of it. If you want to reload for one, you need to be willing to chase the brass, and figure a 25-50% loss rate. If you chose to try a brass deflector, the brass won't go as far. But the ejection speed will beat the hell out of the cases, when they hit the deflector - I figure that's worth a 20-25% damage loss rate, and still 5-10% loss rate for brass that doesn't want to be found. (Much of the "can't find it" losses depend upon where you choose to shoot, of course.)
What about those Wildcats? Knowing that commercial brass had never been produced for it, I went on a search for quotes a couple years ago. I needed .30-06 x 1.550", made from '06 basic brass, and fully reamed for a slightly thinner case wall. It works out to an elongated .45 Win Mag (or
really long .45 Auto), and needs the thinner case wall to be able to expand in the chamber. The '06 case wall is too strong at its normal thickness, and prevents expansion (and the process cannot be done with your average case trimmer/reamer). The only company to give me a quote told me they hadn't produced the brass in more than 10 years, so a run of 5,000 cases would be required to make it worth their time. It would have run me more than $2,500 for the brass. Between the custom dies and the huge lot of brass - the price was too steep.
Even if we reloaders ignore the commercial ammo market... We still weigh other factors.