The sghts are regulated to account for barrel length. The longer barrels have a taller front sight to account for the fact that the bullet spends more time in the barrel, and the longer barrel will rise more during the act of firing.
Not trying to be Deutsche-Bayag
, but if your POA does not equal your POI, it is not the gun. A short-barreled .44 Mag is not a common carry gun, and there are a number of good reasons for that.
To remain proficient with your chosen carry gun will require regular practice. If you choose to carry an exotic/powerful gun, even moreso.
In a real-live SD situation, you will not have time to reconsider and aim 2" (or however much) low.
IMHO, if you cannot shoot your carry gun frequently enough that you are proficient with it, you should carry something that you are proficient with.
I would not (and do not) carry a .44 mag...however, during the winter time I have been known to carry a 4" .357 Mag, .41 Mag or .45 LC. That said, I practice with all of them, and shoot each well.
Your life, your choice...choose wisely.
Edited to add: If you are not carrying it, or using it for SD never mind...but the first paragraph still applies.