I only time I have seen/noticed set back was with my SR 1911. It would only chamber FMJ. Ruined a number of Hollow points with serious set back. The gun was returned for repair and works fine now.
For your question. I leave my guns loaded with one in the chamber. I have chambered some rounds many times and not had a problem. Loading and unloading guns should not be problem if you follow safe practices. If you want to practice and are nervous try snap caps.
For your question. I leave my guns loaded with one in the chamber. I have chambered some rounds many times and not had a problem. Loading and unloading guns should not be problem if you follow safe practices. If you want to practice and are nervous try snap caps.