My new favorite .22 pistol is the S&W 22A. Great sights, easy to clean, and plenty accurate even with cheap bulk .22 ammo. I find the grip angle and the Flash Gordon looks of the Beretta a no-go. The Ruger is a fine pistol, and the grip angle on the 22/45 model is nice, but cleaning it is not fun, even after doing it many, many times.
Any of these will be very accurate and last practically forever. All are reasonably priced.
Any of these will be very accurate and last practically forever. All are reasonably priced.