Any reason you've already stated a preference for 124gr over 115gr, and decided against 147gr? Sounds like you're already on the road to a selection ... which is what you want, and your choice, after all.
That being said ... After seeing & learning the results of gelatin testing hosted by a couple of major manufacturers, as well as reading of numerous tests by the IWBA and other interested folks that are biased to plain results versus hype and sales pitches ...
Please forgive the all-caps words that follow, because I'm really not doing it to be annoying, but ...
What functions best in YOUR weapons? Pistols are machines, after all. Sometimes variance of tolerance and function exists, whether we like it or not.
What are the cost restrictions on YOUR practice versus duty/carry ammunition considerations?
What do you want YOUR ammunition to do in YOUR weapons in situations YOU anticipate YOU might encounter??
Some folks don't want their rounds to penetrate more than 10", some want a minimum of 12", some don't care how far they penetrate, or over-penetrate (remember something's behind your intended target, even if you can't see it, but that's another issue), and some want their rounds to perform in an "ideal" manner in every medium from marshmellow to steel. The circumstances involved in L/E shooting situations can differ quite a bit from civilian self defense shootings.
When it comes to bullet performance (setting aside shooter performance for the moment) I personally prefer the Winchester Ranger T loads in 127gr +P+ ... and yes, it's restricted by Winchester's choice to L/E sales, but it's out there nonetheless ... but then again, in some gelatin testing the Speer Gold Dot 124gr +P and the Remington Golden Saber 124gr +P performed just about as well, depending on what task you set for the rounds, and these rounds aren't restricted by the manufacturers. Even the standard pressure versions did "fine", and if a little more penetration is important to you, the lower velocity loadings sometimes seem to penetrate a little farther (the trade off to a little less expansion). And believe it or not, the Winchester Ranger T load 147gr was right up there with the 127gr +P+ round ... and this was from barrel lengths ranging from 3"- 3 1/2"- 4". Modern engineering & computer design is a wonderful thing ...
Invest some money & time to test fire different ammunition and determine any "preferences" demonstrated by your weapons, and by you. Magic bullets aren't ... magic or real.
Don't forget why we're having this conversation, either ...
While there are many unknowns regarding the psychological reasons for physical incapacitation after suffering a bullet wound, most "authorities" have reached similar conclusions when it comes to the physiological conditions that can cause physical incapacitation after a bullet wound ... blood loss, leading to unconsciousness ... and central nervous system disruption.
I'd be more concerned about the "quality control" of the rounds you shoot & carry, conditions of storage and carry (heat, dampness, excessive exposure to penetrating lubricants, over-pressure potential from rechambering the same round repeatedly and driving it back into the case), and the condition and maintenance of your weapon ... that sort of thing ...
Sorry if I got a little off the subject ... It's not a sensitive issue I hear a lot ... honest.
Get out there and practice, practice, practice ... properly.