A good example is the 260 Remington. On paper this would be an ideal deer cartridge. But Remington in its infantile wisdom decided that the default bullet weight should be 140 grains.
That seems to be slowly changing. Remington is still actively selling the 140gr CoreLokt in 140 but other ammo manufacturers seem to be concentrating on the 120 gr bullets. In fact, since my rifle likes (and is sighted in for) Federal Vital Shoks with the 140 Sierra gameking I have been wanting to stay with those. Unfortunately not one single on-line source I can find has any in stock. Federal still lists them as a stock number but it looks like they may have stopped production.
When my current supply of 140s runs out, it looks like I'm going to have to drop down to 120s.