I've finished off cripples(by other folks) with my GM, and do not regard it as a humane and certain killer in the field over 25 yards. Here in Md, it's below the threshold of legal power.
I also used a 357 Blackhawk with 7 1/2" bbl (legal) to put a 146 gr Speer in the shoulder crease of a meat doe, maybe 20 yards and still. With one of my hunting arrows,a slug, or a ball from a M/L, that placement would have resulted in a bloodtrail of less than 100 yards. Doe died 1/4 mile away, and the trail was sparse in places. Perfect placement, no exit wound.
IOW, not the best choice, and not even a good one...